A unique medical achievement by the research team at the Harvard Medical School. The unseen darkness of the eyes penetrated it to bring back many people who had lost sight. Cell-based medical devices and genetic and tissue engineering had developed rapidly in This area may be a substitute for traditional treatments in the near future, especially in treating corneal aneurysms.
In this article we will learn about one of the achievements of stem cell research: stem cell transplantation.
The experiment began with the implantation of stem cells from the area of ​​the fossa behind the cornea - from healthy corneal tissue to a donor adult - within the eye of a mouse suffering from corneal blindness, and then examined after 5 weeks and also after 13 months to see if the cornea had proliferated or not! The researchers found that these cells have been able to repair corneal damage appeared natural similar to the cornea healthy fish and protein expression.
And now did not move your mind curiosity to know the mechanism of this injury and how to solve their problems ??
The stem cells of the cornea are constantly damaged by infections, infections or even autoimmune diseases. The damage is automatically corrected by stem cells located behind the cornea called limbal stem cells, but many diseases The eye is beyond the ability of the stem cells to keep the cornea transparent; it can lead to poor vision or sometimes blindness.
The only treatment for this problem is the transplantation of new stem cells, either from the patient's healthy eye or from a deceased donor. The stem cell transplantation from the healthy patient's eye is better because the immune system is less likely to reject it.
But what's the problem with applying this technique?
Studies have shown that this process is complex, because finding these cells abundantly in the donor's eye and then identifying them is not an easy process.
To discover this mystery, the researchers were able to identify and label the protein on the surface of the stem cells called ABCB5 and then developed antibodies and markers of stem cells in a sample of human papillomavirus cells, which played an important role To achieve an exclusive purification technique for cells responsible for the successful implantation and repair of the patient's cornea.
"Our findings make it easy to restore the surface of the cornea, and it is a very good example of research that finds its way quickly," said Dr. Bruce Cassander, professor of ophthalmology at Harvard Medical School.
In the previously published work on stem cell stem cells, Natasha Frank, a member of Harvard's HSCI, confirmed that the higher the percentage of stem cells planted, the greater the success, the less chance of success if less than that. .
Finally, it is worth mentioning that a European approval - possibly preliminary - has been issued for a medical product containing stem cells to treat the cornea, which may open the door to promising hope and advanced research.
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